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Tennessee Oncology is home to one of the leading clinical trial networks in the country. We offer a broad menu of trial opportunities in every phase of treatment. Use the search below to discover and learn more about our clinical trials:




90 Results

Specimen Collection Study to Evaluate Biomarkers in Participants with and without Cancer

Condition: Multiple Solid Tumors
TO Study: COLL25004
Clinic: Nashville Breast Center
Protocol: 2021-05

View Details on ClinicalTrials.gov

Specimen Collection Study to Evaluate Biomarkers in Participants with and without Cancer

Condition: Multiple Solid Tumors
TO Study: COLL25004
Clinic: Nashville Breast Center
Protocol: 2021-05

View Details on ClinicalTrials.gov
NCT06356571

A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (SubQSA)

Condition: Multiple Myeloma
TO Study: MM24003
Clinic: Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mount Juliet, Murfreesboro, Skyline, Southern Hills, St. Thomas West, Ringgold, Shelbyville, Smyrna, Chattanooga Downtown, Med Park 2, Memorial, Cleveland, Dalton, Dickson
Protocol: LPS18183

View Details on ClinicalTrials.gov
NCT06121843

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Condition: Multiple Myeloma
TO Study: MM23012
Clinic: Elliston Place Plaza
Protocol: CA088-1005

View Details on ClinicalTrials.gov
NCT06767514

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1 (HARMONi-7)

Condition: Non-small Cell Lung Cancer
TO Study: LUN25082
Clinic: Chattanooga Downtown, Chattanooga East, Cleveland, Dalton, Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Med Park 2, Memorial, Mt. Juliet, Murfreesboro, Ringgold, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West
Protocol: SMT112-3007

View Details on ClinicalTrials.gov
NCT07221474

A Study of V940/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013) (INTerpath-13)

Condition: Non-small Cell Lung Cancer
TO Study: LUN25070
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: V940-013

View Details on ClinicalTrials.gov
NCT07218380

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract (FORAGER-2)

Condition: Urothelial Cancer
TO Study: GU25026
Clinic: Cleveland, Cookeville, Chattanooga Downtown, Dalton, Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Med Park 2, Memorial, Mt. Juliet, Murfreesboro, Ringgold, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West
Protocol: J4G-MC-LZVD

View Details on ClinicalTrials.gov
NCT06784193

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25041
Clinic: Elliston Place Plaza
Protocol: OP-3136-101

View Details on ClinicalTrials.gov
NCT07228832

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer (HARMONi-GI3)

Condition: Colorectal Cancer
TO Study: GI24021
Clinic: Cookeville, Dickson, Elliston Place Plaza, Franklin, Gallatin, Lebanon, Hendersonville, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: SMT112-3005

View Details on ClinicalTrials.gov
NCT07076121

A Study Comparing BMS-986504 in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

Condition: Pancreatic Ductal Adenocarcinoma
TO Study: GI25022
Clinic: Cookeville, Dickson, Elliston Place Plaza, Franklin, Gallatin, Lebanon, Hendersonville, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: CA240-0030

View Details on ClinicalTrials.gov
NCT05536141

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors (ARC-20)

Condition: Renal Cell Carcinoma
TO Study: GU25021
Clinic: Cookeville, Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Chattanooga East
Protocol: AB521

View Details on ClinicalTrials.gov
NCT07361562

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25037
Clinic: Elliston Place Plaza
Protocol: CGT4255-25-101

View Details on ClinicalTrials.gov
NCT06456463

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy (TRILLIUM)

Condition: Acute Myeloid Leukemia
TO Study: AML23001
Clinic: Elliston Place Plaza
Protocol: STEML-401-0423

View Details on ClinicalTrials.gov
NCT05579366

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/PRO1184-001) (RAINFOL-01)

Condition: Endometrial Cancer, Ovarian Cancer
TO Study: MULTI24014
Clinic: Elliston Place Plaza
Protocol: GCT1184-01

View Details on ClinicalTrials.gov
NCT05850234

A Study of GC012F (AZD0120), a CAR T Therapy Targeting CD19 and BCMA in Subjects With Relapsed/Refractory Multiple Myeloma

Condition: Multiple Myeloma
TO Study: MM24010
Clinic: Elliston Place Plaza
Protocol: D8310C00001

View Details on ClinicalTrials.gov
NCT07288359

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Condition: Breast Cancer
TO Study: EPS25030
Clinic: Elliston Place Plaza
Protocol: CGVV858A12101

View Details on ClinicalTrials.gov
NCT05862012

Study of ISB 2001 in Relapsed/?Refractory Multiple Myeloma (TRIgnite-1)

Condition: Multiple Myeloma
TO Study: MM24020
Clinic: Elliston Place Plaza
Protocol: ISB 2001-101

View Details on ClinicalTrials.gov
NCT07353957

Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer
TO Study: LUN25066
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: MCLA-158-CL04

View Details on ClinicalTrials.gov
NCT07100080

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Condition: Non-small Cell Lung Cancer
TO Study: LUN25064
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: CA244-0010

View Details on ClinicalTrials.gov
NCT06745908

ResQ201A: Clinical Trial Of N-803 Plus TISLELIZUMAB And DOCETAXEL Versus DOCETAXEL Monotherapy In Participants With Advanced Or Metastatic Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer
TO Study: LUN24057
Clinic: Lebanon, Cookeville, Hendersonville, Gallatin, Franklin, Med Park 2, Memorial, Mt. Juliet, Murfreesboro, Ringgold, Shelbyville, Skyline, Smyrna, Cleveland, Chattanooga Downtown, Southern Hills, St. Thomas West
Protocol: ResQ201A-NSCLC

View Details on ClinicalTrials.gov
NCT06623422

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/?INTerpath-009)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24039
Clinic: Dickson, Skyline, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: V940-009

View Details on ClinicalTrials.gov
NCT07005154

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

Condition: Prostate Cancer
TO Study: GU24012
Clinic: Chattanooga Downtown, Memorial , Med Park 2
Protocol: 5541-CL-0201

View Details on ClinicalTrials.gov
NCT06784752

Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET (NETTER-3)

Condition: GEP-NET
TO Study: GI24019
Clinic: St. Thomas West, Elliston Place Plaza
Protocol: CAAA601A62301

View Details on ClinicalTrials.gov
NCT06501625

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Condition: Cholangiocarcinoma
TO Study: GI25041
Clinic: Murfreesboro
Protocol: S095031-210

View Details on ClinicalTrials.gov
NCT07224425

A Study in People With Advanced Cancer (Solid Tumours) to Test Different Doses of BI 3810944 and to Find Out Whether it Helps

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25024
Clinic: Elliston Place Plaza
Protocol: 1527-0001

View Details on ClinicalTrials.gov
NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer (OPERA-01)

Condition: Breast Cancer
TO Study: BRE25027
Clinic: Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Midtown, Mt. Juliet, Murfreesboro, Elliston Place Plaza, St. Thomas West, Skyline, Southern Hills, Ringgold, Shelbyville, Smyrna, Chattanooga Downtown, Memorial, Chattanooga East, Med Park 2, Cleveland, Dalton
Protocol: OP-1250-301

View Details on ClinicalTrials.gov
NCT06162221

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Condition: Non-small Cell Lung Cancer
TO Study: MULTI24013
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: RMC-LUNG-101

View Details on ClinicalTrials.gov
NCT05614739

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3 (FORAGER-1)

Condition: Urothelial Cancer
TO Study: MULTI24018
Clinic: Elliston Place Plaza
Protocol: LOXO-FG3-22001

View Details on ClinicalTrials.gov
NCT07123454

A Phase I/?II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (Lumi-NHL)

Condition: Follicular Lymphoma, Large B-Cell Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma
TO Study: LYM24027
Clinic: Elliston Place Plaza
Protocol: D9890C00001

View Details on ClinicalTrials.gov
NCT06465329

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Condition: Non-small Cell Lung Cancer
TO Study: LUN23003
Clinic: Elliston Place Plaza
Protocol: R2810-ONC-2268

View Details on ClinicalTrials.gov
NCT05872295

IKS014 in Advanced Solid Tumors That Express HER2

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25029
Clinic: Elliston Place Plaza
Protocol: IKS014-01

View Details on ClinicalTrials.gov
NCT03424005

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer (Morpheus-panBC)

Condition: Breast Cancer
TO Study: BRE24018
Clinic: Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Midtown, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: CO40115

View Details on ClinicalTrials.gov
NCT07109219

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia (ALLight)

Condition: Acute lymphoblastic leukemia
TO Study: ALL24001
Clinic: Elliston Place Plaza
Protocol: D9891C00001 

View Details on ClinicalTrials.gov
NCT06907043

A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25026
Clinic: Elliston Place Plaza
Protocol: EIK1004-001

View Details on ClinicalTrials.gov
NCT06982521

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer (ReDiscover-2)

Condition: Breast Cancer
TO Study: BRE25026
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Midtown, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Southern Hills, Mt. Juliet
Protocol: RLY-2608-102

View Details on ClinicalTrials.gov
NCT06806033

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/?Refractory Diffuse Large B-Cell Lymphoma

Condition: Large B-Cell Lymphoma
TO Study: LYM24024
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Skyline, Smyrna, Southern Hills, St. Thomas West, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: GO45434

View Details on ClinicalTrials.gov
NCT05211895

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC (PACIFIC-8)

Condition: Non-small Cell Lung Cancer
TO Study: LUN25073
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Skyline, Smyrna, Southern Hills, St. Thomas West, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: D9075C00001

View Details on ClinicalTrials.gov
NCT06074588

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations

Condition: Non-small Cell Lung Cancer
TO Study: LUN24045
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: MK-2870-004

View Details on ClinicalTrials.gov
NCT05061550

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer (NeoCOAST-2)

Condition: Non-small Cell Lung Cancer
TO Study: LUN 494
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Skyline, Smyrna, Southern Hills, St. Thomas West, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: D9077C00001

View Details on ClinicalTrials.gov
NCT07164443

A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC) (KLK2-comPAS)

Condition: Prostate Cancer
TO Study: GU24014
Clinic: Cookeville, Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: 78278343PCR3001  

View Details on ClinicalTrials.gov
NCT06874335

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25022
Clinic: Elliston Place Plaza
Protocol: BHV1530-101

View Details on ClinicalTrials.gov
NCT06943872

A Phase 3 Randomized, Open-Label, Multicenter Study of Sonrotoclax Plus Anti-CD20 Antibody Therapies Versus Venetoclax Plus Rituximab in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Condition: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
TO Study: CLL24007
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: BGB-11417-303

View Details on ClinicalTrials.gov
NCT06112314

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

Condition: Melanoma
TO Study: SKN24005
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, St. Thomas West, Southern Hills
Protocol: PRISM-MEL-301

View Details on ClinicalTrials.gov
NCT05552976

A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)

Condition: Multiple Myeloma
TO Study: MM24009
Clinic: Elliston Place Plaza, Murfreesboro, Smyrna, Chattanooga Downtown, Med Park 2, Memorial
Protocol: CA057-008

View Details on ClinicalTrials.gov
NCT07121946

This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

Condition: Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma
TO Study: LYM24023
Clinic: Elliston Place Plaza
Protocol: LTZ-301-001

View Details on ClinicalTrials.gov
NCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24016
Clinic: Elliston Place Plaza
Protocol: 1479-0012

View Details on ClinicalTrials.gov
NCT06931626

Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer

Condition: Small Cell Lung Cancer
TO Study: LUN25053
Clinic: Elliston Place Plaza
Protocol: PARPA-293-004

View Details on ClinicalTrials.gov
NCT06890598

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer (SUNRAY-02)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24050
Clinic: Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: J3M-MC-JZQH

View Details on ClinicalTrials.gov
NCT06930755

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

Condition: Ovarian Cancer
TO Study: GYN25005
Clinic: Elliston Place Plaza
Protocol: PARPA-293-003

View Details on ClinicalTrials.gov
NCT06667141

Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24015
Clinic: Elliston Place Plaza
Protocol: ACR-2316-101

View Details on ClinicalTrials.gov
NCT06423911

Study of Olverembatinib (HQP1351) in Patients With CP-CML (POLARIS-2)

Condition: Chronic Myeloid Leukemia
TO Study: CML24002
Clinic: Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: HQP1351CG301

View Details on ClinicalTrials.gov
NCT06926920

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

Condition: Breast Cancer
TO Study: BRE24019
Clinic: Elliston Place Plaza, Murfreesboro
Protocol: GS-US-576-7321

View Details on ClinicalTrials.gov
NCT06393374

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR

Condition: Breast Cancer
TO Study: BRE24016
Clinic: Elliston Place Plaza, Lebanon, Smyrna, Southern Hills, Murfreesboro, Mt. Juliet, St. Thomas West, Shelbyville, Chattanooga Downtown, Med Park 2, Memorial
Protocol: MK-2870-012

View Details on ClinicalTrials.gov
NCT06380751

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Condition: Breast Cancer
TO Study: BRE23007
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: D9722C00001

View Details on ClinicalTrials.gov
NCT05714839

A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments (DREAMM-20)

Condition: Multiple Myeloma
TO Study: MM24013
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Mt. Juliet, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: 218670

View Details on ClinicalTrials.gov
NCT06136559

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator’s Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Condition: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
TO Study: CLL23001
Clinic: Dickson, Franklin, Gallatin, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Mt. Juliet, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: MK-1026-011

View Details on ClinicalTrials.gov
NCT04970901

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

Condition: Follicular Lymphoma
TO Study: LYM23001
Clinic: Elliston Place Plaza
Protocol: ADCT-402-105

View Details on ClinicalTrials.gov
NCT06077760

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002) (INTerpath-002)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24037
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Mt. Juliet
Protocol: V940-002

View Details on ClinicalTrials.gov
NCT06252649

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation (CodeBreaK 301)

Condition: Colorectal Cancer
TO Study: GI24010
Clinic: Lebanon, Murfreesboro, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 20210081

View Details on ClinicalTrials.gov
NCT06297226

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (QUINTESSENTIAL)

Condition: Multiple Myeloma
TO Study: MM24014
Clinic: Elliston Place Plaza
Protocol: CA088-1000

View Details on ClinicalTrials.gov
NCT06742996

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/?Refractory Mantle Cell Lymphoma

Condition: Mantle Cell Lymphoma
TO Study: LYM24022
Clinic: St. Thomas West, Elliston Place Plaza, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: BGB-11417-302

View Details on ClinicalTrials.gov
NCT06692738

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24026
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville​, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: D702BC00001

View Details on ClinicalTrials.gov
NCT06246916

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma

Condition: Melanoma
TO Study: SKN23001
Clinic: Murfreesboro, St. Thomas West, Mt. Juliet, Chattanooga Downtown, Med Park 2
Protocol: R3767-ONC-22122

View Details on ClinicalTrials.gov
NCT06119581

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer (SUNRAY-01)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24032
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: J3M-MC-JZQB

View Details on ClinicalTrials.gov
NCT06764485

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator’s Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer (rechARge)

Condition: Prostate Cancer
TO Study: GU24007
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Downtown, Chattanooga East, Dalton, Med Park 2, Memorial, Ringgold
Protocol: CA701-1000

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NCT06492616

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence (ELEGANT)

Condition: Breast Cancer
TO Study: BRE24013
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Southern Hills, Smyrna, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: STML-ELA-0422

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NCT04468061

Saci-IO TNBC: Randomized Phase II Study of Sacituzumab Govitecan With or Without Pembrolizumab in PD-L1-negative Metastatic Triple Negative Breast Cancer (TNBC)

Condition: Breast Cancer
TO Study: BRE 360
Clinic: Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 20-166

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NCT06517875

Phase 2 Open-label Study to Evaluate Momelotinib in Combination with Luspatercept in Participants with Transfusion Dependent Primary or Secondary Myelofibrosis

Condition: Myelofibrosis
TO Study: MPN24004
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 220752

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NCT06479135

A Phase 3, Randomized, Double-blind, Add-on Study Evaluating the Safety and Efficacy of Navtemadlin Plus Ruxolitinib vs Placebo Plus Ruxolitinib in JAK Inhibitor-Naïve Patients with Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

Condition: Myelofibrosis
TO Study: MPN24003
Clinic: Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Dalton, Ringgold, Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Elliston Place Plaza
Protocol: KRT-232-115

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NCT06171685

MMRC HORIZON ONE: A PHASE II RANDOMIZED ADAPTIVE PLATFORM TRIAL EVALUATING NOVEL THERAPIES IN RELAPSED OR REFRACTORY MULTIPLE MYELOMA

Condition: Multiple Myeloma
TO Study: MM24011
Clinic: Elliston Place Plaza, Murfreesboro, Smyrna, Chattanooga Downtown, Med Park 2, Memorial
Protocol: MMRC-099

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NCT06153251

A Phase 1, Open-Label, Dose-Finding Study of BMS-986453, Dual Targeting BCMAxGPRC5D Chimeric Antigen Receptor T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma

Condition: Multiple Myeloma
TO Study: MM23002
Clinic: Elliston Place Plaza
Protocol: CA119-0002

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NCT05722418

Phase 1, Multicenter, Open-Label Study of CB-011, a CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients with Relapsed/Refractory Multiple Myeloma (CAMMOUFLAGE Trial)

Condition: Multiple Myeloma
TO Study: MM 161
Clinic: Elliston Place Plaza
Protocol: CB-011

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NCT05651932

A Phase 1 Study of KTX-1001, an Oral, First-In-Class, Selective, and Potent MMSET Catalytic Inhibitor that Suppresses H3K36me2 in Patients with Relapsed and Refractory Multiple Myeloma

Condition: Multiple Myeloma
TO Study: MM 159
Clinic: Elliston Place Plaza
Protocol: K36 MMSET-001

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NCT05006716

A Phase 1/2, Open-Label, Dose-Escalation and -Expansion Study of the Bruton Tyrosine Kinase-Targeted Protein-Degrader BGB-16673 in Patients With B-Cell Malignancies

Condition: Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Waldenstrom Macroglobulinemia
TO Study: LYM23005
Clinic: Elliston Place Plaza
Protocol: BGB-16673-101

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NCT05605899

An Adaptive Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Axicabtagene Ciloleucel versus Standard of Care Treatment as First-Line Therapy in Subjects with High-Risk Large B-Cell Lymphoma (ZUMA-23)

Condition: Large B-Cell Lymphoma
TO Study: LYM 206
Clinic: Elliston Place Plaza
Protocol: KT-US-484-0136

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NCT04830137

A Phase 1, Dose Escalation, Safety and Tolerability Study of NX-2127, a Bruton’s Tyrosine Kinase (BTK) Degrader, in Adults with Relapsed/Refractory B-cell Malignancies.

Condition: Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Primary Central Nervous System Lymphoma, Small Lymphocytic Lymphoma, Waldenstrom Macroglobulinemia
TO Study: LYM 184
Clinic: Elliston Place Plaza
Protocol: NX-2127

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NCT06472245

A randomized, open-label, phase 3 trial comparing the efficacy and safety of OSE2101 versus docetaxel in HLA-A2 positive patients with metastatic Non-Small Cell Lung Cancer (NSCLC) and secondary resistance to Immune Checkpoint Inhibitor (ICI)- ARTEMIA…

Condition: Non-small Cell Lung Cancer
TO Study: LUN24016
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville​, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: OSE2101

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NCT06496178

A Phase 3 Open-label, Randomized Controlled Study to Evaluate the Efficacy and Safety of Petosemtamab Compared with Investigator’s Choice Monotherapy Treatment in Previously Treated Patients with Incurable, Metastatic/recurrent Head and Neck Squamous Cell Carcinoma

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN23003
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: MCLA-158-CL02

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NCT06525220

A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR – HN1)

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN24004
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Southern Hills, Mt. Juliet, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: MCLA-158-CL03

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NCT06727565

A Phase 2 Platform Study of Novel Combination Therapies in Participants with Head and Neck Squamous Cell Carcinoma

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN24005
Clinic: St. Thomas West
Protocol: GS-US-699-7184

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NCT06497556

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer
TO Study: LUN23013
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills
Protocol: BO45217

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NCT06417814

A Phase III, Open-label, Sponsor-blind, Randomized Study of Dato DXd With or Without Osimertinib Versus Platinum-based Doublet Chemotherapy for Participants with EGFR-mutated Locally Advanced or Metastatic Non-small Cell Lung Cancer whose Disease has Progressed on…

Condition: Non-small Cell Lung Cancer
TO Study: LUN24015
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Mt. Juliet
Protocol: D516KC00001

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NCT06627647

A Phase III, Randomized, Double-Blind, Multicenter, Global Study of Rilvegostomig in Combination with Chemotherapy for First-line Treatment of Patients with Metastatic Non-squamous Non-Small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung03)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24029
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville​, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: D702FC00001

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NCT06256588

A Randomized, Double-blind, Placebo-controlled Phase 3 Study to evaluate Dostarlimab as Sequential Therapy after Chemoradiation in Participants with Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma (JADE)

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN23002
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: 221530

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NCT06750094

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/?NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy (OrigAMI-3)

Condition: Colorectal Cancer
TO Study: GI24012
Clinic: Elliston Place Plaza, Murfreesboro, Smyrna, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 61186372COR3002

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NCT06028074

First-in-Human, Open-Label, Phase 1/2 Dose-Escalation with Enrichment and Dose-Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of GIM-122 as a Single Agent in Adult Subjects with Advanced Solid Malignancies

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24006
Clinic: Elliston Place Plaza
Protocol: GIM122-CT01

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NCT06425926

Phase 1/2, Open-label, Multi-center Study of the Safety, Tolerability, and Efficacy of GIM-531 as a Single Agent and in Combination with Anti-PD-1 in Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24005
Clinic: Elliston Place Plaza
Protocol: GIM531-CT01

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NCT06150664

A Phase 1, Open-Label, Multiple-Ascending Dose Study of the Safety and Tolerability of CTX-8371 in Patients with Advanced Malignancies

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24002
Clinic: Elliston Place Plaza
Protocol: CTX-8371-001

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NCT04862663

A Phase Ib/III Open-label, Randomised Study of Capivasertib plus CDK4/6 Inhibitors and Fulvestrant versus CDK4/6 Inhibitors and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced, Unresectable or Metastatic Breast Cancer…

Condition: Breast Cancer
TO Study: BRE24011
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville
Protocol: D361DC00001

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NCT06103864

A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared with Investigator’s Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients with PD-L1 Positive…

Condition: Breast Cancer
TO Study: BRE23006
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: D7630C00001

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