Skip to main content

Find a Trial

Tennessee Oncology is home to one of the leading clinical trial networks in the country. We offer a broad menu of trial opportunities in every phase of treatment. Use the search below to discover and learn more about our clinical trials:




85 Results

Specimen Collection Study to Evaluate Biomarkers in Participants with and without Cancer?

Condition:
TO Study: COLL25004
Clinic: Nashville Breast Center
Protocol: 2021-05

View Details on ClinicalTrials.gov

Specimen Collection Study to Evaluate Biomarkers in Participants with and without Cancer?

Condition:
TO Study: COLL25004
Clinic: Nashville Breast Center
Protocol: 2021-05

View Details on ClinicalTrials.gov
NCT05862012

Study of ISB 2001 in Relapsed/?Refractory Multiple Myeloma (TRIgnite-1)

Condition: Multiple Myeloma
TO Study: MM24020
Clinic: Elliston Place Plaza
Protocol: ISB 2001-101

View Details on ClinicalTrials.gov
NCT07353957

Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer
TO Study: LUN25066
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: MCLA-158-CL04

View Details on ClinicalTrials.gov
NCT07100080

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Condition: Non-small Cell Lung Cancer
TO Study: LUN25064
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: CA244-0010

View Details on ClinicalTrials.gov
NCT06745908

ResQ201A: Clinical Trial Of N-803 Plus TISLELIZUMAB And DOCETAXEL Versus DOCETAXEL Monotherapy In Participants With Advanced Or Metastatic Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer
TO Study: LUN24057
Clinic: Lebanon, Cookeville, Hendersonville, Gallatin, Franklin, Med Park 2, Memorial, Mt. Juliet, Murfreesboro, Ringgold, Shelbyville, Skyline, Smyrna, Cleveland, Chattanooga Downtown, Southern Hills, St. Thomas West
Protocol: ResQ201A-NSCLC

View Details on ClinicalTrials.gov
NCT06623422

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/?INTerpath-009)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24039
Clinic: Dickson, Skyline, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: V940-009

View Details on ClinicalTrials.gov
NCT06784752

Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET (NETTER-3)

Condition: GEP-NET
TO Study: GI24019
Clinic: St. Thomas West, Elliston Place Plaza
Protocol: CAAA601A62301

View Details on ClinicalTrials.gov
NCT06501625

Ivosidenib Plus Durvalumab and Gemcitabine/?Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Condition: Cholangiocarcinoma
TO Study: GI25041
Clinic: Murfreesboro
Protocol: S095031-210

View Details on ClinicalTrials.gov
NCT07005154

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

Condition: Prostate Cancer
TO Study: GU24012
Clinic: Chattanooga Downtown, Memorial , Med Park 2
Protocol: 5541-CL-0201

View Details on ClinicalTrials.gov
NCT07224425

A Study in People With Advanced Cancer (Solid Tumours) to Test Different Doses of BI 3810944 and to Find Out Whether it Helps

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25024
Clinic: Elliston Place Plaza
Protocol: 1527-0001

View Details on ClinicalTrials.gov

Specimen Collection Study to Evaluate Biomarkers in Participants with and without Cancer?

Condition:
TO Study: COLL25004
Clinic: Nashville Breast Center
Protocol: 2021-05

View Details on ClinicalTrials.gov
NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/?HER2- Advanced Breast Cancer (OPERA-01)

Condition: Breast Cancer
TO Study: BRE25027
Clinic: Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Midtown, Mt. Juliet, Murfreesboro, Elliston Place Plaza, St. Thomas West, Skyline, Southern Hills, Ringgold, Shelbyville, Smyrna, Chattanooga Downtown, Memorial, Chattanooga East, Med Park 2, Cleveland, Dalton
Protocol: OP-1250-301

View Details on ClinicalTrials.gov
NCT06162221

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Condition: Non-small Cell Lung Cancer
TO Study: MULTI24013
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: RMC-LUNG-101

View Details on ClinicalTrials.gov
NCT05614739

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3 (FORAGER-1)

Condition: Urothelial Cancer
TO Study: MULTI24018
Clinic: Elliston Place Plaza
Protocol: LOXO-FG3-22001

View Details on ClinicalTrials.gov

Specimen Collection Study to Evaluate Biomarkers in Participants with and without Cancer​

Condition:
TO Study: COLL25004
Clinic: Nashville Breast Center
Protocol: 2021-05

View Details on ClinicalTrials.gov
NCT07123454

A Phase I/?II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/?Refractory B-cell Non-Hodgkin Lymphoma (Lumi-NHL)

Condition: Follicular Lymphoma, Large B-Cell Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma
TO Study: LYM24027
Clinic: Elliston Place Plaza
Protocol: D9890C00001

View Details on ClinicalTrials.gov
NCT06745323

A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC (DeLLphi-309)

Condition: Small Cell Lung Cancer
TO Study: LUN24038
Clinic: St. Thomas West, Dickson, Skyline, Hendersonville, Southern Hills, Franklin, Lebanon, Murfreesboro, Gallatin, Shelbyville, Mt. Juliet, Smyrna
Protocol: 20240092

View Details on ClinicalTrials.gov
NCT06465329

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Condition: Non-small Cell Lung Cancer
TO Study: LUN23003
Clinic: Elliston Place Plaza
Protocol: R2810-ONC-2268

View Details on ClinicalTrials.gov
NCT05872295

IKS014 in Advanced Solid Tumors That Express HER2

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25029
Clinic: Elliston Place Plaza
Protocol: IKS014-01

View Details on ClinicalTrials.gov
NCT03424005

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer (Morpheus-panBC)

Condition: Breast Cancer
TO Study: BRE24018
Clinic: Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Midtown, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: CO40115

View Details on ClinicalTrials.gov
NCT07109219

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia (ALLight)

Condition: Acute lymphoblastic leukemia
TO Study: ALL24001
Clinic: Elliston Place Plaza
Protocol: D9891C00001 

View Details on ClinicalTrials.gov
NCT06907043

A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25026
Clinic: Elliston Place Plaza
Protocol: EIK1004-001

View Details on ClinicalTrials.gov
NCT06982521

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/?HER2- Breast Cancer (ReDiscover-2)

Condition: Breast Cancer
TO Study: BRE25026
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Midtown, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Southern Hills, Mt. Juliet
Protocol: RLY-2608-102

View Details on ClinicalTrials.gov
NCT06018337

A Study of DB-1303/?BNT323 vs Investigator’s Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)

Condition: Breast Cancer
TO Study: BRE24015
Clinic: Dickson, Franklin, Gallatin, Midtown, Mt. Juliet, Murfreesboro, Chattanooga Downtown, Memorial
Protocol: DB-1303-O-3002

View Details on ClinicalTrials.gov
NCT06806033

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/?Refractory Diffuse Large B-Cell Lymphoma

Condition: Large B-Cell Lymphoma
TO Study: LYM24024
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Skyline, Smyrna, Southern Hills, St. Thomas West, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: GO45434

View Details on ClinicalTrials.gov
NCT05211895

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC (PACIFIC-8)

Condition: Non-small Cell Lung Cancer
TO Study: LUN25073
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Skyline, Smyrna, Southern Hills, St. Thomas West, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: D9075C00001

View Details on ClinicalTrials.gov
NCT06074588

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations

Condition: Non-small Cell Lung Cancer
TO Study: LUN24045
Clinic: Dickson, Skyline, Hendersonville, Southern Hills, St. Thomas West, Franklin, Mt. Juliet, Elliston Place Plaza, Lebanon, Shelbyville, Murfreesboro, Gallatin, Smyrna, Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Ringgold, Dalton
Protocol: MK-2870-004

View Details on ClinicalTrials.gov
NCT05061550

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer (NeoCOAST-2)

Condition: Non-small Cell Lung Cancer
TO Study: LUN 494
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Skyline, Smyrna, Southern Hills, St. Thomas West, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: D9077C00001

View Details on ClinicalTrials.gov
NCT07164443

A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC) (KLK2-comPAS)

Condition: Prostate Cancer
TO Study: GU24014
Clinic: Cookeville, Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: 78278343PCR3001  

View Details on ClinicalTrials.gov
NCT06874335

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS25022
Clinic: Elliston Place Plaza
Protocol: BHV1530-101

View Details on ClinicalTrials.gov
NCT06943872

A Phase 3 Randomized, Open-Label, Multicenter Study of Sonrotoclax Plus Anti-CD20 Antibody Therapies Versus Venetoclax Plus Rituximab in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Condition: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
TO Study: CLL24007
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, Southern Hills, St. Thomas West, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: BGB-11417-303

View Details on ClinicalTrials.gov
NCT06112314

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

Condition: Melanoma
TO Study: SKN24005
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, Shelbyville, Skyline, Smyrna, St. Thomas West, Southern Hills
Protocol: PRISM-MEL-301

View Details on ClinicalTrials.gov
NCT05552976

A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2) (SUCCESSOR-2)

Condition: Multiple Myeloma
TO Study: MM24009
Clinic: Elliston Place Plaza, Murfreesboro, Smyrna, Chattanooga Downtown, Med Park 2, Memorial
Protocol: CA057-008

View Details on ClinicalTrials.gov
NCT07121946

This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

Condition: Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma
TO Study: LYM24023
Clinic: Elliston Place Plaza
Protocol: LTZ-301-001

View Details on ClinicalTrials.gov
NCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24016
Clinic: Elliston Place Plaza
Protocol: 1479-0012

View Details on ClinicalTrials.gov
NCT06931626

Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer

Condition: Small Cell Lung Cancer
TO Study: LUN25053
Clinic: Elliston Place Plaza
Protocol: PARPA-293-004

View Details on ClinicalTrials.gov
NCT06890598

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer (SUNRAY-02)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24050
Clinic: Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: J3M-MC-JZQH

View Details on ClinicalTrials.gov
NCT06930755

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

Condition: Ovarian Cancer
TO Study: GYN25005
Clinic: Elliston Place Plaza
Protocol: PARPA-293-003

View Details on ClinicalTrials.gov
NCT06667141

Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24015
Clinic: Elliston Place Plaza
Protocol: ACR-2316-101

View Details on ClinicalTrials.gov
NCT06423911

Study of Olverembatinib (HQP1351) in Patients With CP-CML (POLARIS-2)

Condition: Chronic Myeloid Leukemia
TO Study: CML24002
Clinic: Dickson, Elliston Place Plaza, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: HQP1351CG301

View Details on ClinicalTrials.gov
NCT04246086

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma

Condition: Follicular Lymphoma
TO Study: LYM24017
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Mt. Juliet, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: CO41942

View Details on ClinicalTrials.gov
NCT06926920

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

Condition: Breast Cancer
TO Study: BRE24019
Clinic: Elliston Place Plaza, Murfreesboro
Protocol: GS-US-576-7321

View Details on ClinicalTrials.gov
NCT06393374

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR

Condition: Breast Cancer
TO Study: BRE24016
Clinic: Elliston Place Plaza, Lebanon, Smyrna, Southern Hills, Murfreesboro, Mt. Juliet, St. Thomas West, Shelbyville, Chattanooga Downtown, Med Park 2, Memorial
Protocol: MK-2870-012

View Details on ClinicalTrials.gov
NCT06380751

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/?6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/? ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Condition: Breast Cancer
TO Study: BRE23007
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: D9722C00001

View Details on ClinicalTrials.gov
NCT05714839

A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments (DREAMM-20)

Condition: Multiple Myeloma
TO Study: MM24013
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Mt. Juliet, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: 218670

View Details on ClinicalTrials.gov
NCT06136559

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator’s Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/? Small Lymphocytic Lymphoma (SLL)

Condition: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
TO Study: CLL23001
Clinic: Dickson, Franklin, Gallatin, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Mt. Juliet, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: MK-1026-011

View Details on ClinicalTrials.gov
NCT04970901

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

Condition: Follicular Lymphoma
TO Study: LYM23001
Clinic: Elliston Place Plaza
Protocol: ADCT-402-105

View Details on ClinicalTrials.gov
NCT06077760

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002) (INTerpath-002)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24037
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Mt. Juliet
Protocol: V940-002

View Details on ClinicalTrials.gov
NCT06691984

Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer

Condition: Prostate Cancer
TO Study: GU24006
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills
Protocol: 20230005

View Details on ClinicalTrials.gov
NCT06252649

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation (CodeBreaK 301)

Condition: Colorectal Cancer
TO Study: GI24010
Clinic: Lebanon, Murfreesboro, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 20210081

View Details on ClinicalTrials.gov
NCT06297226

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (QUINTESSENTIAL)

Condition: Multiple Myeloma
TO Study: MM24014
Clinic: Elliston Place Plaza
Protocol: CA088-1000

View Details on ClinicalTrials.gov
NCT06742996

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/?Refractory Mantle Cell Lymphoma

Condition: Mantle Cell Lymphoma
TO Study: LYM24022
Clinic: St. Thomas West, Elliston Place Plaza, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: BGB-11417-302

View Details on ClinicalTrials.gov
NCT06692738

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24026
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville​, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: D702BC00001

View Details on ClinicalTrials.gov
NCT06246916

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma

Condition: Melanoma
TO Study: SKN23001
Clinic: Murfreesboro, St. Thomas West, Mt. Juliet, Chattanooga Downtown, Med Park 2
Protocol: R3767-ONC-22122

View Details on ClinicalTrials.gov
NCT06119581

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer (SUNRAY-01)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24032
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: J3M-MC-JZQB

View Details on ClinicalTrials.gov
NCT06764485

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator’s Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer (rechARge)

Condition: Prostate Cancer
TO Study: GU24007
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Downtown, Chattanooga East, Dalton, Med Park 2, Memorial, Ringgold
Protocol: CA701-1000

View Details on ClinicalTrials.gov
NCT06492616

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence (ELEGANT)

Condition: Breast Cancer
TO Study: BRE24013
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Mt. Juliet, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Southern Hills, Smyrna, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: STML-ELA-0422

View Details on ClinicalTrials.gov
NCT06369285

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer (ALISCA-Breast1)

Condition: Breast Cancer
TO Study: BRE23008
Clinic: Elliston Place Plaza, Murfreesboro, Mt. Juliet, Shelbyville, Smyrna, Chattanooga Downtown, Med Park 2, Memorial
Protocol: PUMA-ALI-1201

View Details on ClinicalTrials.gov
NCT04468061

Saci-IO TNBC: Randomized Phase II Study of Sacituzumab Govitecan With or Without Pembrolizumab in PD-L1-negative Metastatic Triple Negative Breast Cancer (TNBC)

Condition: Breast Cancer
TO Study: BRE 360
Clinic: Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 20-166

View Details on ClinicalTrials.gov
NCT06517875

Phase 2 Open-label Study to Evaluate Momelotinib in Combination with Luspatercept in Participants with Transfusion Dependent Primary or Secondary Myelofibrosis

Condition: Myelofibrosis
TO Study: MPN24004
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Cleveland, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 220752

View Details on ClinicalTrials.gov
NCT06153251

A Phase 1, Open-Label, Dose-Finding Study of BMS-986453, Dual Targeting BCMAxGPRC5D Chimeric Antigen Receptor T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma

Condition: Multiple Myeloma
TO Study: MM23002
Clinic: Elliston Place Plaza
Protocol: CA119-0002

View Details on ClinicalTrials.gov
NCT05651932

A Phase 1 Study of KTX-1001, an Oral, First-In-Class, Selective, and Potent MMSET Catalytic Inhibitor that Suppresses H3K36me2 in Patients with Relapsed and Refractory Multiple Myeloma

Condition: Multiple Myeloma
TO Study: MM 159
Clinic: Elliston Place Plaza
Protocol: K36 MMSET-001

View Details on ClinicalTrials.gov
NCT05722418

Phase 1, Multicenter, Open-Label Study of CB-011, a CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients with Relapsed/Refractory Multiple Myeloma (CAMMOUFLAGE Trial)

Condition: Multiple Myeloma
TO Study: MM 161
Clinic: Elliston Place Plaza
Protocol: CB-011

View Details on ClinicalTrials.gov
NCT06171685

MMRC HORIZON ONE: A PHASE II RANDOMIZED ADAPTIVE PLATFORM TRIAL EVALUATING NOVEL THERAPIES IN RELAPSED OR REFRACTORY MULTIPLE MYELOMA

Condition: Multiple Myeloma
TO Study: MM24011
Clinic: Elliston Place Plaza, Murfreesboro, Smyrna, Chattanooga Downtown, Med Park 2, Memorial
Protocol: MMRC-099

View Details on ClinicalTrials.gov
NCT06479135

A Phase 3, Randomized, Double-blind, Add-on Study Evaluating the Safety and Efficacy of Navtemadlin Plus Ruxolitinib vs Placebo Plus Ruxolitinib in JAK Inhibitor-Naïve Patients with Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

Condition: Myelofibrosis
TO Study: MPN24003
Clinic: Cleveland, Chattanooga Downtown, Med Park 2, Memorial, Dalton, Ringgold, Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Elliston Place Plaza
Protocol: KRT-232-115

View Details on ClinicalTrials.gov
NCT05006716

A Phase 1/2, Open-Label, Dose-Escalation and -Expansion Study of the Bruton Tyrosine Kinase-Targeted Protein-Degrader BGB-16673 in Patients With B-Cell Malignancies

Condition: Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Waldenstrom Macroglobulinemia
TO Study: LYM23005
Clinic: Elliston Place Plaza
Protocol: BGB-16673-101

View Details on ClinicalTrials.gov
NCT05605899

An Adaptive Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Axicabtagene Ciloleucel versus Standard of Care Treatment as First-Line Therapy in Subjects with High-Risk Large B-Cell Lymphoma (ZUMA-23)

Condition: Large B-Cell Lymphoma
TO Study: LYM 206
Clinic: Elliston Place Plaza
Protocol: KT-US-484-0136

View Details on ClinicalTrials.gov
NCT04830137

A Phase 1, Dose Escalation, Safety and Tolerability Study of NX-2127, a Bruton’s Tyrosine Kinase (BTK) Degrader, in Adults with Relapsed/Refractory B-cell Malignancies.

Condition: Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Primary Central Nervous System Lymphoma, Small Lymphocytic Lymphoma, Waldenstrom Macroglobulinemia
TO Study: LYM 184
Clinic: Elliston Place Plaza
Protocol: NX-2127

View Details on ClinicalTrials.gov
NCT04224493

Symphony-1: A Phase 1b/3 Double-Blind, Randomized, Active-Controlled, 3-Stage, Biomarker Adaptive Study Of Tazemetostat Or Placebo In Combination With Lenalidomide Plus Rituximab In Subjects With Relapsed/Refractory Follicular Lymphoma

Condition: Follicular Lymphoma
TO Study: LYM 170
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Elliston Place Plaza
Protocol: EZH-302

View Details on ClinicalTrials.gov
NCT06497556

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer
TO Study: LUN23013
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills
Protocol: BO45217

View Details on ClinicalTrials.gov
NCT06496178

A Phase 3 Open-label, Randomized Controlled Study to Evaluate the Efficacy and Safety of Petosemtamab Compared with Investigator’s Choice Monotherapy Treatment in Previously Treated Patients with Incurable, Metastatic/recurrent Head and Neck Squamous Cell Carcinoma

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN23003
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: MCLA-158-CL02

View Details on ClinicalTrials.gov
NCT06525220

A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR – HN1)

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN24004
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Southern Hills, Mt. Juliet, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: MCLA-158-CL03

View Details on ClinicalTrials.gov
NCT06727565

A Phase 2 Platform Study of Novel Combination Therapies in Participants with Head and Neck Squamous Cell Carcinoma

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN24005
Clinic: St. Thomas West
Protocol: GS-US-699-7184

View Details on ClinicalTrials.gov
NCT06417814

A Phase III, Open-label, Sponsor-blind, Randomized Study of Dato DXd With or Without Osimertinib Versus Platinum-based Doublet Chemotherapy for Participants with EGFR-mutated Locally Advanced or Metastatic Non-small Cell Lung Cancer whose Disease has Progressed on…

Condition: Non-small Cell Lung Cancer
TO Study: LUN24015
Clinic: Elliston Place Plaza, Dickson, Franklin, Gallatin, Hendersonville, Lebanon, Murfreesboro, St. Thomas West, Shelbyville, Skyline, Smyrna, Southern Hills, Mt. Juliet
Protocol: D516KC00001

View Details on ClinicalTrials.gov
NCT06472245

A randomized, open-label, phase 3 trial comparing the efficacy and safety of OSE2101 versus docetaxel in HLA-A2 positive patients with metastatic Non-Small Cell Lung Cancer (NSCLC) and secondary resistance to Immune Checkpoint Inhibitor (ICI)- ARTEMIA…

Condition: Non-small Cell Lung Cancer
TO Study: LUN24016
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville​, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: OSE2101

View Details on ClinicalTrials.gov
NCT06627647

A Phase III, Randomized, Double-Blind, Multicenter, Global Study of Rilvegostomig in Combination with Chemotherapy for First-line Treatment of Patients with Metastatic Non-squamous Non-Small Cell Lung Cancer Whose Tumors Express PD-L1 (TC ? 1%) (ARTEMIDE-Lung03)

Condition: Non-small Cell Lung Cancer
TO Study: LUN24029
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville​, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial
Protocol: D702FC00001

View Details on ClinicalTrials.gov
NCT06256588

A Randomized, Double-blind, Placebo-controlled Phase 3 Study to evaluate Dostarlimab as Sequential Therapy after Chemoradiation in Participants with Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma (JADE)

Condition: Head and Neck Squamous Cell Carcinoma
TO Study: HN23002
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: 221530

View Details on ClinicalTrials.gov
NCT06750094

A Study of Amivantamab and FOLFIRI Versus Cetuximab/?Bevacizumab and FOLFIRI in Participants With KRAS/?NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy (OrigAMI-3)

Condition: Colorectal Cancer
TO Study: GI24012
Clinic: Elliston Place Plaza, Murfreesboro, Smyrna, Chattanooga Downtown, Med Park 2, Memorial
Protocol: 61186372COR3002

View Details on ClinicalTrials.gov
NCT06028074

First-in-Human, Open-Label, Phase 1/2 Dose-Escalation with Enrichment and Dose-Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of GIM-122 as a Single Agent in Adult Subjects with Advanced Solid Malignancies

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24006
Clinic: Elliston Place Plaza
Protocol: GIM122-CT01

View Details on ClinicalTrials.gov
NCT06425926

Phase 1/2, Open-label, Multi-center Study of the Safety, Tolerability, and Efficacy of GIM-531 as a Single Agent and in Combination with Anti-PD-1 in Advanced Solid Tumors

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24005
Clinic: Elliston Place Plaza
Protocol: GIM531-CT01

View Details on ClinicalTrials.gov
NCT06777316

A First-in-Human Study of a Selective FGFR2/3 Inhibitor, CGT4859, in Patients with Cholangiocarcinoma and Other Advanced Solid Tumors

Condition: Biliary Tract Cancer, Relapsed or Refractory Solid Tumors
TO Study: EPS24004
Clinic: Elliston Place Plaza
Protocol: CGT4859-24-101

View Details on ClinicalTrials.gov
NCT06150664

A Phase 1, Open-Label, Multiple-Ascending Dose Study of the Safety and Tolerability of CTX-8371 in Patients with Advanced Malignancies

Condition: Relapsed or Refractory Solid Tumors
TO Study: EPS24002
Clinic: Elliston Place Plaza
Protocol: CTX-8371-001

View Details on ClinicalTrials.gov
NCT04862663

A Phase Ib/III Open-label, Randomised Study of Capivasertib plus CDK4/6 Inhibitors and Fulvestrant versus CDK4/6 Inhibitors and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced, Unresectable or Metastatic Breast Cancer…

Condition: Breast Cancer
TO Study: BRE24011
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville
Protocol: D361DC00001

View Details on ClinicalTrials.gov
NCT06103864

A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared with Investigator’s Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients with PD-L1 Positive…

Condition: Breast Cancer
TO Study: BRE23006
Clinic: Elliston Place Plaza, Lebanon, Skyline, Smyrna, Dickson, Southern Hills, Franklin, Murfreesboro, Mt. Juliet, Gallatin, St. Thomas West, Hendersonville, Shelbyville, Cleveland, Chattanooga Downtown, Dalton, Med Park 2, Memorial, Ringgold
Protocol: D7630C00001

View Details on ClinicalTrials.gov